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- サプライヤー
- AcroBioSystems
- カタログNo.
- PON-M82E4
- 製品名称
- Biotinylated Mouse Podocalyxin Protein, His,Avitag? (HPLC verified)
- タンパク質名
- Podocalyxin
- Species
- Mouse
- HOST
- HEK293
Overview
| Synonyms | - |
|---|---|
| Characteristics | This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag?). The protein has a calculated MW of 43.3 kDa. The protein migrates as 95-140 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation. |
| Endotoxin Level | N/A |
| Purity | 90% |
| Description | Podocalyxin is a heavily glycosylated transmembrane sialoprotein belonging to the CD34 family of cell surface molecules. It is primarily expressed in renal glomerular podocytes, where it plays a critical role in maintaining the integrity of the glomerular filtration barrier through charge-dependent repulsion and modulation of podocyte foot process architecture. The protein’s large extracellular domain, rich in sialic acid residues, mediates interactions with other molecules, influencing cell signaling and migration. Its multifunctional role makes it a potential biomarker and therapeutic target in both renal diseases and cancer research. |
| Reference | - |
| URL | https://www.acrobiosystems.com/products/protein/podocalyxin-mouse-pon-m82e4 |
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