リコンビナントタンパク質
ACROBiosystems社 プロダクトリスト:Recombinant Protein
- サプライヤー
- AcroBioSystems
- カタログNo.
- PLU-H5229
- 製品名称
- Human PLAU / uPA Protein, His Tag
- タンパク質名
- PLAU
- Species
- Human
- HOST
- HEK293
Overview
Synonyms | - |
---|---|
Characteristics | Human PLAU, His Tag is fused with a polyhistidine tag at the C-terminus, and has a calculated MW of 47.2 kDa. The protein migrates as 45-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.<br> <strong>Please note that the protein is not activated by protease digestion. In vitro activation is generally recommended for higher activity.</strong> |
Endotoxin Level | 1.0 EU per μg |
Purity | 92% |
Description | Urokinase - type plasminogen activator is also known as PLAU and UPA, a serine protease with an extremely limited substrate specificity, cleaving the sequence Cys ? Pro ? Gly - Arg560 - Val561 ? Val ? Gly ? Gly ? Cys in plasminogen to form plasmin. uPA is a potent marker of invasion and metastasis in a variety of human cancers associated with breast, stomach, colon, bladder, ovary, brain and endometrium.uPA and its receptor (uPAR) have been implicated in a broad spectrum of pathophysiological processes, including fibrinolysis, proteolysis, inflammation, atherogenesis and plaque destabilization, all of which are involved in the pathogenesis of MI (myocardial infarction). |
Reference | - |
URL | https://www.acrobiosystems.com/P424-Human-PLAU--uPA-Protein-His-Tag.html |