Human Hyaluronidase PH-20 / SPAM1 Protein, Tag Free (active enzyme, MALS verified) [PH0-H5219]

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サプライヤー: AcroBioSystems
カタログNo.: PH0-H5219
製品名称: Human Hyaluronidase PH-20 / SPAM1 Protein, Tag Free (active enzyme, MALS verified)
タンパク質名: Hyaluronidase PH-20
Species: Human
HOST: HEK293

Synonyms	-
Characteristics	This protein carries no "tag". The protein has a calculated MW of 52.6 kDa. The protein migrates as 65-70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level	0.1 EU per μg
Purity	95%
Description	Hyaluronidase PH-20 is also known as Sperm adhesion molecule 1 (SPAM1) and Sperm surface protein PH-20, which belongs to the glycosyl hydrolase 56 family, SPAM1 / PH-20 is expressed in testis. SPAM-1 / PH20 random hydrolysis of (1->4)-linkages between N ? acetyl ? beta ? D ? glucosamine and D-glucuronate residues in hyaluronate. SPAM-1 / PH20 involved in sperm-egg adhesion. Upon fertilization sperm must first penetrate a layer of cumulus cells that surrounds the egg before reaching the zona pellucida. The cumulus cells are embedded in a matrix containing hyaluronic acid which is formed prior to ovulation. SPAM1 aids in penetrating the layer of cumulus cells by digesting hyaluronic acid.
Reference	-
URL	https://www.acrobiosystems.com/products/protein/hyaluronidase-ph-20-human-ph0-h5219

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