Human Progranulin Protein, His Tag, low endotoxin (MALS & SPR verified) [PGN-H52H3]

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サプライヤー: AcroBioSystems
カタログNo.: PGN-H52H3
製品名称: Human Progranulin Protein, His Tag, low endotoxin (MALS & SPR verified)
タンパク質名: Progranulin
Species: Human
HOST: HEK293

Synonyms	-
Characteristics	This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 63.7 kDa. The protein migrates as 80-95 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level	0.01 EU per μg
Purity	95%
Description	Progranulin, a secreted glycoprotein, is encoded in humans by the single GRN gene. Progranulin consists of seven and a half, tandemly repeated, non-identical copies of the 12 cysteine granulin motif. Many cellular processes and diseases are associated with this unique pleiotropic factor that include, but are not limited to, embryogenesis, tumorigenesis, inflammation, wound repair, neurodegeneration and lysosome function. Haploinsufficiency caused by autosomal dominant mutations within the GRN gene leads to frontotemporal lobar degeneration, a progressive neuronal atrophy that presents in patients as frontotemporal dementia.
Reference	-
URL	https://www.acrobiosystems.com/products/protein/progranulin-human-pgn-h52h3

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