タンパク質、抗体、アッセイキット
タンパク質カタログ
- サプライヤー
- AcroBioSystems
- カタログNo.
- PD2-H82E8
- 製品名称
- Biotinylated Human PD-L2 / B7-DC Protein, Avitag?,His Tag (recommended for biopanning)
- タンパク質名
- PD-L2
- Species
- Human
- HOST
- HEK293
Overview
Synonyms | - |
---|---|
Characteristics | This protein carries an Avi tag (Avitag?) at the C-terminus, followed by a polyhistidine tag. The protein has a calculated MW of 25.2 kDa. The protein migrates as 33-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Endotoxin Level | 1.0 EU per μg |
Purity | 95% |
Description | Programmed cell death 1 ligand 2 (PD-L2 or PDCD1 ligand 2) is also known as Butyrophilin B7-DC, CD antigen CD273, which belongs to the immunoglobulin superfamily or BTN/MOG family. The expression of PD-L2 is up-regulated by IFNG/IFN-gamma stimulation in monocytes and induced on dendritic cells grown from peripheral blood mononuclear cells with CSF2 and IL-4. PD-L2 Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. PD-L2 interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production. |
Reference | - |
URL | https://www.acrobiosystems.com/P2102-Biotinylated-Human-PD-L2--B7-DC-Protein-Avitag%E2%84%A2His-Tag-%28recommended-for-biopanning%29.html |