Biotinylated Human PD-L1 / B7-H1 Protein, Fc,Avitag?,His Tag (MALS verified) [PD1-H82F3]

サプライヤー: AcroBioSystems
カタログNo.: PD1-H82F3
製品名称: Biotinylated Human PD-L1 / B7-H1 Protein, Fc,Avitag?,His Tag (MALS verified)
タンパク質名: PD-L1
Species: Human
HOST: HEK293

Synonyms	-
Characteristics	This protein carries a human IgG1 Fc fragment at the C-terminus, followed by a polyhistidine tag. The Avi tag (Avitag?) is inserted in-between the Fc and his tags. The protein has a calculated MW of 54.0 kDa. The protein migrates as 65-80 kDa on a SDS-PAGE gel when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition due to glycosylation.
Endotoxin Level	1.0 EU per μg
Purity	95%
Description	Programmed cell death 1 ligand 1 (PDL1) is also known as B7-H, B7H1, MGC142294, MGC142296, PD-L1, PDCD1L1 and PDCD1LG1,which is a member of the growing B7 family of immune molecules and is involved in the regulation of cellular and humoral immune responses.PDL1 is a cell surface immunoglobulin superfamily with two Ig-like domains within the extracellular region and a short cytoplasmic domain. This protein is broadly expressed in the majority of peripheral tissues as well as hematopoietic cells. Interaction between PDL1 and its receptors belonging to the CD28 family of molecules provide both stimulatory and inhibitory signals in regulating T cell activation and tolerance. PDL1 may inhibit ongoing T-cell responses by inducing apoptosis and arresting cell-cycle progression.
Reference	-
URL	https://www.acrobiosystems.com/P1396-Biotinylated-Human-PD-L1--B7-H1-Protein-FcAvitag%E2%84%A2His-Tag-%28MALS-verified%29.html

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