Biotinylated Human PCSK9 (D374Y) Protein, Avitag?,His Tag [PCY-H82E7]

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Synonyms	-
Characteristics	This protein carries an Avi tag (Avitag?) at the C-terminus, followed by a polyhistidine tag. This protein undergoes autocatalytic cleavage to release the pro-peptide and mature chain. The pro-peptide and mature chain are associated through non?covalent interactions and with a calculated MW of 13.8 kDa and 59.9 kDa respectively. The protein migrates as 15kDa, 65kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation. The D374Y mutation results in higher affinity of PCSK9 for LDLR.
Endotoxin Level	N/A
Purity	95%
Description	MABSol? Biotinylated Human PCSK9 (D374Y), Avitag,His Tag (PCY-H82E7) is expressed from human HEK293 cells. It contains AA Gln 31 - Gln 692 (Accession # Q8NBP7-1 (D374Y)).
Reference	-
URL	https://www.acrobiosystems.com/products/protein/pcsk9-human-pcy-h82e7

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