Biotinylated Cynomolgus / Rhesus macaque OX40 Ligand / TNFSF4 Protein, His,Avitag? [OXL-C52Q3]

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サプライヤー: AcroBioSystems
カタログNo.: OXL-C52Q3
製品名称: Biotinylated Cynomolgus / Rhesus macaque OX40 Ligand / TNFSF4 Protein, His,Avitag?
タンパク質名: OX40 Ligand
Species: Cynomolgus / Rhesus macaque
HOST: HEK293

Synonyms	-
Characteristics	This protein carries a polyhistidine tag at the N-terminus, followed by an Avi tag (Avitag?). The protein has a calculated MW of 51.0 kDa. The protein migrates as 55-65 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under non-reducing (NR) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level	N/A
Purity	85%
Description	Tumor necrosis factor ligand superfamily member 4 (TNFSF4) is also known as glycoprotein Gp34, OX40 ligand (OX40L), TAX transcriptionally-activated glycoprotein 1 and CD252, which belongs to the tumor necrosis factor family. TNFSF4 is the ligand for CD134 and is expressed on such cells as DC2s (a subtype of dendritic cells) enabling amplification of Th2 cell differentiation. The interaction of TNFSF4-TNFSF4 is involved in the pathogenesis of multiple autoimmune and inflammatory diseases such as systemic lupus erythematosus (SLE), carotid artery disease and cancer. Furthermore, similar to other TNF superfamily members, membrane-bound OX40 Ligand (TNFSF4) exists as a homotrimer. Human TNFSF4 shares 46% amino acid sequence identity with its mouse counterpart.
Reference	-
URL	https://www.acrobiosystems.com/products/protein/ox40-ligand-cynomolgus-rhesus-macaque-oxl-c52q3

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