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タンパク質カタログ
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- サプライヤー
- AcroBioSystems
- カタログNo.
- NYR-H5258
- 製品名称
- Human NY-ESO-1 TCR Protein, Fc Tag (MALS & SPR verified)
- タンパク質名
- NY-ESO-1 TCR
- Species
- Human
- HOST
- HEK293
Overview
| Synonyms | - |
|---|---|
| Characteristics | This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 49.3 kDa & 53.2 kDa. The protein migrates as 60-80 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation. |
| Endotoxin Level | 1.0 EU per μg |
| Purity | 90% |
| Description | NY-ESO-1 is one of the most recognized tumor antigens in immunotherapy. Its expression is strictly limited to male germ cells and multiple malignant tumor cells, with virtually no presence in normal somatic cells. This unique expression profile makes it an ideal target for T-cell receptor (TCR) therapy. NY-ESO-1 specific TCR can bind to NY-ESO-1 peptides presented by MHC molecules, and clinical trials have demonstrated significant efficacy of NY-ESO-1 targeted TCR-T therapy in advanced sarcomas and other malignancies. |
| Reference | 3687 |
| URL | https://www.acrobiosystems.com/products/protein/ny-eso-1-tcr-human-nyr-h5258 |
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