タンパク質、抗体、アッセイキット
タンパク質カタログ
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- サプライヤー
- AcroBioSystems
- カタログNo.
- NR2-H82E3
- 製品名称
- Biotinylated Human Neuropilin-2 / NRP2 Protein, His,Avitag? (MALS verified)
- タンパク質名
- Neuropilin-2
- Species
- Human
- HOST
- HEK293
Overview
| Synonyms | - |
|---|---|
| Characteristics | This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag?). The protein has a calculated MW of 98.7 kDa. The protein migrates as 130-150 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation. |
| Endotoxin Level | N/A |
| Purity | 90% |
| Description | Neuropilin-1 (Npn-1, previously known as neuropilin) and Neuropilin-2 (previously known as Npn-1-related molecule) are type I transmembrane proteins that bind distinct members of the class III secreted semaphorin subfamily that are implicated in repulsive axon guidance. Neuropilin extracellular domains contain two CUB (complement-binding) domains, two domains with homology to coagulation factors V and VIII, and a MAM (meprin) domain. In the absence of ligands, neuropilins can form homo- and hetero-oligomers via their MAM domains. Expression in developing neurons of the central and peripheral nervous systems is somewhat overlapping but distinct. Npn-1 and Npn-2 are also receptors for VEGF165 on endothelial and tumor cells. |
| Reference | - |
| URL | https://www.acrobiosystems.com/products/protein/neuropilin-2-human-nr2-h82e3 |

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