Human NK2R Full Length Protein, Flag,His Tag (Detergent) [NKR-H52D3]

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Synonyms	-
Characteristics	This protein carries a flag tag at the N-terminus and a polyhistidine tag at the C-terminus. The protein has a calculated MW of 47.9 kDa. The protein migrates as 53-55 kDa and 65-70 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level	N/A
Purity	90%
Description	NK2R is a G protein-coupled receptor with high affinity for the tachykinin Substance K (Neurokinin A). Upon activation, it triggers a phosphatidylinositol-calcium signaling pathway, leading to intracellular calcium release. The receptor's binding affinity follows the order: Substance K > Neuromedin K > Substance P. NK2R also regulates energy metabolism and has shown significant potential in appetite control. Due to its diverse functions, it is considered a promising therapeutic target for conditions such as asthma, irritable bowel syndrome, obesity, and type 2 diabetes.
Reference	-
URL	https://www.acrobiosystems.com/products/protein/nk2r-human-nkr-h52d3

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