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- サプライヤー
- AcroBioSystems
- カタログNo.
- NKC-C5247
- 製品名称
- Cynomolgus NKG2C / CD159c Protein, His Tag
- タンパク質名
- NKG2C
- Species
- Cynomolgus
- HOST
- HEK293
Overview
| Synonyms | - |
|---|---|
| Characteristics | This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 17.8 kDa. The protein migrates as 25 kDa, 27-30 kDa and 35-110 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
| Endotoxin Level | 1.0 EU per μg |
| Purity | 85% |
| Description | Human NKG2C (NK cell Group 2 isoform C; Killer cell lectin-like receptor subfamily C, member 2) is a member of the C-type lectin-like superfamily of proteins. NKG2C plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. The CD94/NKG2C killer lectin-like receptor (KLR) specific for HLA-E is coupled to the KARAP/DAP12 adapter in a subset of NK cells, triggering their effector functions. CD94/NKG2C may operate as an alternative activation pathway for a subset of CD8+ T lymphocytes, triggering their effector functions and proliferation upon specific ligand engagement. |
| Reference | - |
| URL | https://www.acrobiosystems.com/products/protein/nkg2c-cynomolgus-nkc-c5247 |
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