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- サプライヤー
- AcroBioSystems
- カタログNo.
- NE4-H5255
- 製品名称
- Human Nectin-4 Protein, Fc Tag (MALS verified)
- タンパク質名
- Nectin-4
- Species
- Human
- HOST
- HEK293
Overview
| Synonyms | - |
|---|---|
| Characteristics | This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 60.5 kDa. The protein migrates as 65-70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
| Endotoxin Level | 0.1 EU per μg |
| Purity | 95% |
| Description | Nectin-4 (gene name PVRL4, poliovirus receptor-like 4) is a 66 kDa type I transmembrane glycoprotein belonging to the Nectin family of Ig superfamily proteins. Nectins are cell adhesion molecules that play a key role in various biological processes such as polarity, proliferation, differentiation and migration, for epithelial, endothelial, immune and neuronal cells, during development and adult life. Nectin-4 is a tumor-associated antigen in 50%, 49% and 86%o of breast, ovarian and lung carcinomas, respectively, mostly on tumors of bad prognosis. Its expression is not detected in the corresponding normal tissues. |
| Reference | - |
| URL | https://www.acrobiosystems.com/products/protein/nectin-4-human-ne4-h5255 |
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