リコンビナントタンパク質
ACROBiosystems社 プロダクトリスト:Recombinant Protein
- サプライヤー
- AcroBioSystems
- カタログNo.
- NC4-H5253
- 製品名称
- Human NKG2A&CD94 Protein, Mouse IgG2a Fc Tag (MALS verified)
- タンパク質名
- NKG2A & CD94
- Species
- Human
- HOST
- HEK293
Overview
Synonyms | - |
---|---|
Characteristics | This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 55.5 kDa. The protein migrates as 65-80 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Endotoxin Level | 0.1 EU per μg |
Purity | 95% |
Description | CD94 plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. NKG2A/CD159a is a transmembrane protein belonging to the CD94/NKG2 family of C-type lectin-like receptors that inhibits innate immune system activation. CD94 pairs with the NKG2 molecule as a heterodimer. The CD94/NKG2 complex, on the surface of natural killer cells interacts with Human Leukocyte Antigen (HLA)-E on target cells. |
Reference | - |
URL | https://www.acrobiosystems.com/P3073-Human-NKG2ACD94-Protein-Mouse-IgG2a-Fc-Tag-%28MALS-verified%29.html |