リコンビナントタンパク質
ACROBiosystems社 プロダクトリスト:Recombinant Protein
- サプライヤー
- AcroBioSystems
- カタログNo.
- MU1-H52H9
- 製品名称
- Human Mucin-1 / MUC-1 (890-1158) Protein, His Tag
- タンパク質名
- Mucin-1
- Species
- Human
- HOST
- HEK293
Overview
Synonyms | - |
---|---|
Characteristics | This protein carries a polyhistidine tag at the C-terminus. The mature form of Mucin-1 is a non-covalent heterodimeric complex with the proteolytically cleaved partial α and partial β chain. Each partial α and partial β chain has a calculated MW of 21.3 kDa (partial α chain) and 8.4 kDa (partial β chain). The protein migrates as 45-80 kDa (partial α chain) and 10 kDa (partial β chain) under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Endotoxin Level | 1.0 EU per μg |
Purity | 90% |
Description | Membrane mucins have several functions in epithelial cells including cytoprotection, extravasation during metastases, maintenance of luminal structure, and signal transduction. MUC17, contains an extended, repetitive extracellular glycosylation domain and a carboxyl terminus with two EGF-like domains, a SEA module domain, a transmembrane domain, and a cytoplasmic domain with potential serine and tyrosine phosphorylation sites. Interacts via its C-terminus with PDZK1 and this interaction appears important for proper localization. Probably plays a role in maintaining homeostasis on mucosal surfaces. |
Reference | - |
URL | https://www.acrobiosystems.com/P2987-Human-Mucin-1--MUC-1-%28890-1158%29-Protein-His-Tag.html |