Human Mucin-1 / MUC-1 Protein, Llama IgG2b Fc Tag, low endotoxin [MU1-H5255]

Synonyms	-
Characteristics	This protein carries a llama IgG2b Fc tag at the C-terminus. The protein has a calculated MW of 42.4 kDa. The protein migrates as 50-70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level	0.01 EU per μg
Purity	90%
Description	Membrane mucins have several functions in epithelial cells including cytoprotection, extravasation during metastases, maintenance of luminal structure, and signal transduction. MUC17, contains an extended, repetitive extracellular glycosylation domain and a carboxyl terminus with two EGF-like domains, a SEA module domain, a transmembrane domain, and a cytoplasmic domain with potential serine and tyrosine phosphorylation sites. Interacts via its C-terminus with PDZK1 and this interaction appears important for proper localization. Probably plays a role in maintaining homeostasis on mucosal surfaces.
Reference	-
URL	https://www.acrobiosystems.com/P2901-Human-Mucin-1--MUC-1-Protein-Llama-IgG2b-Fc-Tag-low-endotoxin.html

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