Cynomolgus MASP2 Protein, His Tag [MA2-C51H3]

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Synonyms	-
Characteristics	This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 45.6 kDa. The protein migrates as 42-45 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE).
Endotoxin Level	1.0 EU per μg
Purity	90%
Description	Mannan-binding lectin-associated serine protease 2 (MASP-2) is a member of the lectin pathway of complement and is one of two splice products from the MASP2 gene. The protein is secreted from the liver as a zymogenic protein consisting of 671 residues and circulates at a concentration of approximately 0.41 μg/mL in the serum. MASP-2 is associated with pattern-recognition molecules as a homodimer that is activated by MASP-1 when bound to an activating surface resulting in an A-chain and a B-chain linked by a disulphide bond. MASP-2 is also capable of autoactivating. Activated MASP-2 cleaves C2 and C4, which leads to formation of the C3 convertase, C4b2a, and activation of complement.
Reference	3328
URL	https://www.acrobiosystems.com/products/protein/masp2-cynomolgus-ma2-c51h3

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