Human Lymphotoxin alpha1/beta2 Protein, Fc Tag (MALS verified) [LY2-H5263]

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Synonyms	-
Characteristics	This protein carries a human IgG1 Fc tag at the N-terminus. The protein has a calculated MW of 78.3 kDa. The protein migrates as 65-95 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level	1.0 EU per μg
Purity	90%
Description	Lymphotoxin alpha1/bate2 (LT α1/β1) are members of the tumor necrosis factor (TNF) superfamily, and plays a pivotal role in the establishment and regulation of the immune system. The predominant form on the lymphocyte surface is the lymphotoxin alpha 1/beta 2 complex (e.g. 1 molecule alpha/2 molecules beta) and this complex is the primary ligand for the lymphotoxin beta receptor (LTβR). The minor complex is lymphotoxin alpha 2/beta 1. Lymphotoxin alpha mediates a large variety of inflammatory, immunostimulatory, and antiviral responses, is involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. Genetic variations in this gene are associated with susceptibility to leprosy type 4, myocardial infarction, non-Hodgkin's lymphoma, and psoriatic arthritis. Lymphotoxin beta is an inducer of the inflammatory response system and involved in normal development of lymphoid tissue.
Reference	-
URL	https://www.acrobiosystems.com/products/protein/lymphotoxin-alpha1-beta2-human-ly2-h5263

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