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- サプライヤー
- AcroBioSystems
- カタログNo.
- LO1-H5243
- 製品名称
- Human LOX-1 Protein, His Tag (MALS verified)
- タンパク質名
- LOX-1
- Species
- Human
- HOST
- HEK293
Overview
| Synonyms | - |
|---|---|
| Characteristics | This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 26.4 kDa. The protein migrates as 30-40 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation. |
| Endotoxin Level | 0.05 EU per μg |
| Purity | 90% |
| Description | LOX-1 is a transmembrane glycoprotein that binds to and internalizes ox-LDL.LOX-1 gene deletion in mice and anti-LOX-1 therapy has been shown to decrease inflammation, oxidative stress and atherosclerosis. LOX-1 deletion also results in damage from ischemia, making LOX-1 a promising target of therapy for atherosclerosis and related disorders. In this article we focus on the different mechanisms for regulation, signaling and the various effects of LOX-1 in contributing to atherosclerosis. |
| Reference | 3260 |
| URL | https://www.acrobiosystems.com/products/protein/lox-1-human-lo1-h5243 |
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