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ACROBiosystems社 プロダクトリスト：Recombinant Protein
- サプライヤー
- AcroBioSystems
- カタログNo.
- LIT-C5244
- 製品名称
- Cynomolgus LIGHT / TNFSF14 Protein, His Tag, active trimer (MALS verified)
- タンパク質名
- LIGHT
- Species
- Cynomolgus
- HOST
- HEK293
Overview
| Synonyms | - |
|---|---|
| Characteristics | This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 58.6 kDa. The protein migrates as 63-66 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation. |
| Endotoxin Level | 1.0 EU per μg |
| Purity | 90% |
| Description | Tumor necrosis factor ligand superfamily member 14(LIGHT) is a tumor necrosis factor (TNF) superfamily ligand that regulates T cell immune responses by signaling through the herpes virus entry mediator (HVEM) and the lymphotoxin beta receptor (LTbetaR). LIGHT has emerged as a potent initiator of T cell co-stimulation signals effecting CTL-mediated tumor rejection, allograft rejection and graft versus host disease. Constitutive expression of LIGHT leads to tissue destruction and autoimmune-like disease syndromes. |
| Reference | - |
| URL | https://www.acrobiosystems.com/P6505-Cynomolgus-LIGHT--TNFSF14-Protein-His-Tag-active-trimer-%28MALS-verified%29.html |
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