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タンパク質カタログ
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- サプライヤー
- AcroBioSystems
- カタログNo.
- LG5-H52H3
- 製品名称
- Human LGR5?/?GPR49 protein, His Tag
- タンパク質名
- LGR5
- Species
- Human
- HOST
- HEK293
Overview
| Synonyms | - |
|---|---|
| Characteristics | This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 62.0 kDa. The protein migrates as 65-75 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation. |
| Endotoxin Level | N/A |
| Purity | 90% |
| Description | LGR5 (also known as GPR49) is a seven-transmembrane protein of the class A Rhodopsin-like family of GPCRs. LGR5 and LGR4 bind the R-spondins with high affinity and mediate the potentiation of Wnt/β-catenin signaling by enhancing Wnt-induced LRP6 phosphorylation. The LGR5/RSPO complex could promote Wnt signalling via the neutralization of two transmembrane E3 ligases, RNF43 and ZNRF3. |
| Reference | - |
| URL | https://www.acrobiosystems.com/products/protein/lgr5-human-lg5-h52h3 |
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