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- サプライヤー
- AcroBioSystems
- カタログNo.
- LG5-C52H7
- 製品名称
- Cynomolgus LGR5?/?GPR49 protein, His Tag
- タンパク質名
- LGR5
- Species
- Cynomolgus
- HOST
- HEK293
Overview
| Synonyms | - |
|---|---|
| Characteristics | This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 61.7 kDa. The protein migrates as 66-70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
| Endotoxin Level | 1.0 EU per μg |
| Purity | 95% |
| Description | LGR5 (also known as GPR49) is a seven-transmembrane protein of the class A Rhodopsin-like family of GPCRs. LGR5 and LGR4 bind the R-spondins with high affinity and mediate the potentiation of Wnt/β-catenin signaling by enhancing Wnt-induced LRP6 phosphorylation. The LGR5/RSPO complex could promote Wnt signalling via the neutralization of two transmembrane E3 ligases, RNF43 and ZNRF3. |
| Reference | - |
| URL | https://www.acrobiosystems.com/products/protein/lgr5-cynomolgus-lg5-c52h7 |
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