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- サプライヤー
- AcroBioSystems
- カタログNo.
- LCB-H82Q3
- 製品名称
- Biotinylated Human LC3B Protein, Avitag?,His Tag (MALS verified)
- タンパク質名
- LC3B
- Species
- Human
- HOST
- E. coli
Overview
| Synonyms | - |
|---|---|
| Characteristics | This protein carries an Avi tag (Avitag?) at the N-terminus, followed by a polyhistidine tag. The protein has a calculated MW of 18.4 kDa. The protein migrates as 19-20 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE). |
| Endotoxin Level | N/A |
| Purity | 90% |
| Description | LC3B is a pivotal protein encoded by the MAP1LC3B gene, widely recognized as a core component and indicator of cellular autophagy. It plays an essential role in autophagosome formation and the regulation of the autophagic degradation pathway. Critically, the conversion of cytosolic LC3B-I to lipidated, autophagosome-associated LC3B-II upon autophagy activation serves as a robust and widely used biochemical hallmark for assessing autophagic activity. |
| Reference | - |
| URL | https://www.acrobiosystems.com/products/protein/lc3b-human-lcb-h82q3 |
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