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タンパク質(癌免疫療法用)

ACROBiosystems社 プロダクトリスト:Recombinant Protein

サプライヤー
AcroBioSystems
カタログNo.
LA3-H52Aa
製品名称
Human LAG-3 / CD223 Protein, Mouse IgG2a Fc Tag
タンパク質名
LAG-3
Species
Human
HOST
HEK293
100ug: 74,000円
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1mg: 486,000円
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Overview

Synonyms LAG3,CD223,FDC
Characteristics This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 73.3 kDa. The protein migrates as 90-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level Less than 1.0 EU per μg by the LAL method.
Purity >95% as determined by SDS-PAGE.
Description Lymphocyte activation gene 3 protein (LAG3) is also known as CD antigen CD223 and protein FDC, which belongs to immunoglobulin (Ig) superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4. LAG3 /CD223 involved in lymphocyte activation. LAG3 /CD223 binds to HLA class-II antigens.
Reference (1) Triebel F., et al., 1990, J. Exp. Med. 171:1393-1405.
(2) Baixeras E., et al., 1992, J. Exp. Med. 176:327-337.
URL https://www.acrobiosystems.com/P2377-Human-LAG-3--CD223-Protein-Mouse-IgG2a-Fc-Tag.html

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