Human Kallikrein 9 Protein, His Tag [KL9-H52H3]

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Synonyms	-
Characteristics	This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 27.9 kDa. The protein migrates as 35-45 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level	1.0 EU per μg
Purity	90%
Description	Kallikrein 9 (KLK9) is a member of the human tissue kallikrein-related peptidase family, encoded by the KLK9 gene on chromosome 19q13.41. It is a secreted serine protease synthesized as an inactive zymogen and activated by proteolytic cleavage. KLK9 is expressed in several tissues, including the brain, skin, and reproductive organs, and is thought to participate in extracellular matrix remodeling and epithelial homeostasis. Biochemical studies show that KLK9 is a chymotrypsin-like enzyme with preference for tyrosine at the P1 site, regulated by metal ions and protease inhibitors. Dysregulated KLK9 expression has been linked to cancers and inflammatory conditions, suggesting potential biomarker and therapeutic relevance.
Reference	3113
URL	https://www.acrobiosystems.com/products/protein/kallikrein-9-human-kl9-h52h3

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