Human Kallikrein 8 / KLK-8 Protein, His Tag (active enzyme, MALS verified) [KL8-H52H3]

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サプライヤー: AcroBioSystems
カタログNo.: KL8-H52H3
製品名称: Human Kallikrein 8 / KLK-8 Protein, His Tag (active enzyme, MALS verified)
タンパク質名: Kallikrein 8
Species: Human
HOST: HEK293

Synonyms	-
Characteristics	This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 26.8 kDa. The protein migrates as 32-35 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level	1.0 EU per μg
Purity	95%
Description	Kallikrein 8 (KLK8), also known as Neuropsin, PRSS19, or TADG-14, is a member of the human kallikrein-related peptidase family located on chromosome 19. It is a secreted serine protease with strong expression in the hippocampus, where it regulates synaptic plasticity, learning, and memory through cleavage of extracellular matrix proteins and neural adhesion molecules. KLK8 has also been implicated in skin physiology, including keratinocyte proliferation and desquamation. Abnormal expression of KLK8 has been reported in several cancers, such as ovarian and colorectal cancer, making it a potential biomarker and therapeutic target2.
Reference	3112
URL	https://www.acrobiosystems.com/products/protein/kallikrein-8-human-kl8-h52h3

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