検索リコンビナントタンパク質
ACROBiosystems社 プロダクトリスト：Recombinant Protein
- サプライヤー
- AcroBioSystems
- カタログNo.
- IT3-R52E2
- 製品名称
- Rat Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer Protein, His Tag&Tag Free (MALS verified)
- タンパク質名
- Integrin alpha V beta 3
- Species
- Rat
- HOST
- HEK293
Overview
| Synonyms | - |
|---|---|
| Characteristics | Rat ITGAV&ITGB3 Heterodimer, His Tag&Tag Free, has a calculated MW of 112.3 kDa (ITGAV) & 81.6 kDa (ITGB3). Subunit ITGAV is fused with an acidic tail at the C-terminus and followed by a polyhistidine tag and subunit ITGB3 contains no tag but a basic tail at the C-terminus. |
| Endotoxin Level | 1.0 EU per μg |
| Purity | 95% |
| Description | Integrin alpha-V/beta-3 (ITGAV:ITGB3) is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. Integrins alpha-IIb/beta-3 and alpha-V/beta-3 recognize the sequence R-G-D in a wide array of ligands. Also, Integrin alpha-V/beta-3 acts as a receptor for herpes virus 8/HHV-8, coxsackievirus A9, Hantaan virus, cytomegalovirus/HHV-5, human metapneumovirus, human parechovirus 1 and west nile virus. Furthermore, in case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. |
| Reference | - |
| URL | https://www.acrobiosystems.com/P5331-Rat-Integrin-alpha-V-beta-3-%28ITGAVITGB3%29-Heterodimer-Protein-His-TagTag-Free-%28MALS-verified%29.html |
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