タンパク質、抗体、アッセイキット
タンパク質カタログ
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- サプライヤー
- AcroBioSystems
- カタログNo.
- IT3-M52W3
- 製品名称
- Mouse Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer Protein, His Tag&Tag Free (MALS verified)
- タンパク質名
- Integrin alpha V beta 3
- Species
- Mouse
- HOST
- HEK293
Overview
| Synonyms | - |
|---|---|
| Characteristics | This protein . The protein has a calculated MW of 112.5 kDa | 81.6 kDa. The protein migrates as 95-105 kDa, 120-130 kDa and 140-160 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation. |
| Endotoxin Level | 1.0 EU per μg |
| Purity | 95% |
| Description | Integrin alpha-V/beta-3 (ITGAV:ITGB3) is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. Integrins alpha-IIb/beta-3 and alpha-V/beta-3 recognize the sequence R-G-D in a wide array of ligands. Also, Integrin alpha-V/beta-3 acts as a receptor for herpes virus 8/HHV-8, coxsackievirus A9, Hantaan virus, cytomegalovirus/HHV-5, human metapneumovirus, human parechovirus 1 and west nile virus. Furthermore, in case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. |
| Reference | 3047 |
| URL | https://www.acrobiosystems.com/products/protein/integrin-alpha-v-beta-3-mouse-it3-m52w3 |

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