Cynomolgus Integrin alpha X beta 2 (ITGAX&ITGB2) Heterodimer Protein, His Tag&Tag Free [IT2-C52W3]

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サプライヤー: AcroBioSystems
カタログNo.: IT2-C52W3
製品名称: Cynomolgus Integrin alpha X beta 2 (ITGAX&ITGB2) Heterodimer Protein, His Tag&Tag Free
タンパク質名: Integrin alpha X beta 2
Species: Cynomolgus
HOST: HEK293

Synonyms	-
Characteristics	Cynomolgus ITGAX&ITGB2 Heterodimer Protein, His Tag&Tag Free, produced by co-expression of ITGAX and ITGB2, has a calculated MW of 125.9 kDa (ITGAX) and 78.0 kDa (ITGB2). Subunit ITGAX is fused with an acidic tail at the C-terminus and followed by a polyhistidine tag and subunit ITGB2 contains no tag but a basic tail at the C-terminus. The protein migrates as 150-180 kDa (ITGAX) and 95-100 kDa (ITGB2) when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level	1.0 EU per μg
Purity	90%
Description	The integrin αXβ2 takes a key role in host defense and functions as a receptor for the complement C3 cleavage product iC3b, fibrinogen, denatured proteins, and intercellular adhesion molecule (ICAM)-1. Integrin αXβ2 αXβ2 has a unique cellular distribution with expression on monocytes, macrophages, and the CD8? subsets of dendritic cells and involves in priming and regulation of the immune response.
Reference	-
URL	https://www.acrobiosystems.com/products/protein/integrin-alpha-x-beta-2-cynomolgus-it2-c52w3

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