検索リコンビナントタンパク質
ACROBiosystems社 プロダクトリスト：Recombinant Protein
- サプライヤー
- AcroBioSystems
- カタログNo.
- IT1-R53Wb
- 製品名称
- Rat Integrin alpha 3 beta 1 (ITGA3&ITGB1) Heterodimer Protein, His Tag&Tag Free (MALS verified)
- タンパク質名
- Integrin alpha 3 beta 1
- Species
- Rat
- HOST
- CHO
Overview
| Synonyms | - |
|---|---|
| Characteristics | Rat ITGA3 & ITGB1 Heterodimer Protein, His Tag&Tag Free, has a calculated MW of 113.4 kDa (ITGA3) & 83.7 kDa (ITGB1). Subunit ITGA3 is fused with an acidic tail at the C-terminus and followed by a polyhistidine tag and subunit ITGB1 contains no tag but a basic tail at the C-terminus. The non-reducing (NR) protein migrates as 125-150 kDa (ITGA3) and 100-110 kDa (ITGB1) respectively due to glycosylation. |
| Endotoxin Level | 1.0 EU per μg |
| Purity | 90% |
| Description | Integrin alpha-3/beta-1 is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. Integrin alpha-3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration. |
| Reference | - |
| URL | https://www.acrobiosystems.com/P6478-Rat-Integrin-alpha-3-beta-1-%28ITGA3ITGB1%29-Heterodimer-Protein-His-TagTag-Free-%28MALS-verified%29.html |
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