リコンビナントタンパク質
ACROBiosystems社 プロダクトリスト:Recombinant Protein
- サプライヤー
- AcroBioSystems
- カタログNo.
- IT1-H52Wc
- 製品名称
- Human Integrin alpha 3 beta 1 (ITGA3&ITGB1) Heterodimer Protein, His Tag&Tag Free (MALS verified)
- タンパク質名
- Integrin alpha 3 beta 1
- Species
- Human
- HOST
- HEK293
Overview
Synonyms | - |
---|---|
Characteristics | Human ITGA3&ITGB1 Heterodimer Protein, His Tag&Tag Free, produced by co-expression of ITGA3 and ITGB1, has a calculated MW of 133.3 kDa (ITGA3) and 83.7 kDa (ITGB1). Subunit ITGA3 is fused with an acidic tail at the C-terminus and followed by a polyhistidine tag and subunit ITGB1 contains no tag but a basic tail at the C-terminus. The non-reducing (NR) protein migrates as 125-150 kDa (ITGA3) and 100-110 kDa (ITGB1) respectively due to glycosylation. |
Endotoxin Level | 1.0 EU per μg |
Purity | 90% |
Description | Integrin alpha-3/beta-1 is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. Integrin alpha-3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration. |
Reference | - |
URL | https://www.acrobiosystems.com/P3039-Human-Integrin-alpha-3-beta-1-%28ITGA3ITGB1%29-Heterodimer-Protein-His-TagTag-Free-%28MALS-verified%29.html |