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ACROBiosystems社 プロダクトリスト:Recombinant Protein

サプライヤー
AcroBioSystems
カタログNo.
IT1-H52W7
製品名称
Human Integrin alpha 6 beta 1 (ITGA6&ITGB1) Heterodimer Protein
タンパク質名
Integrin alpha 6 beta 1
Species
Human
HOST
HEK293
100ug: 87,000円
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1mg: 605,000円
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Overview

Synonyms Integrin alpha 6 beta 1,ITGA6B1,ITGA6&ITGB1,ITGA6&B1
Characteristics Human ITGA6 & ITGB1 Heterodimer Protein, produced by co-expression of ITGA6 and ITGB1, has a calculated MW of 116.8 kDa (ITGA6) and 83.7 kDa (ITGB1). Subunit ITGA6 is fused with an acidic tail at the C-terminus and followed by a polyhistidine tag and sub
Endotoxin Level Less than 1.0 EU per μg by the LAL method.
Purity >90% as determined by SDS-PAGE.
Description Integrin alpha 6 beta 1, also called platelet glycoprotein GPIc-IIa, is a receptor for laminin on platelets. The ITGA6 protein product is the integrin alpha chain alpha 6. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, alpha 6 may combine with beta 4 in the integrin referred to as TSP180, or with beta 1 in the integrin VLA-6. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. ITGA6 has been shown to interact with TSPAN4 and GIPC1.
Reference (1) Tachibana I, et al., 1997, The Journal of Biological Chemistry, 272 (46): 29181-29189.
(2) Tani TT, et al., 2001, The Journal of Biological Chemistry, 276 (39): 36535-36542.
(3) Lipscomb EA, etal., 2005, Cancer Metastasis Reviews, 24 (3): 413-423.
URL https://www.acrobiosystems.com/P2368-Human-Integrin-alpha-6-beta-1-%28ITGA6ITGB1%29-Heterodimer-Protein.html

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