Cynomolgus Integrin alpha 3 beta 1 (ITGA3&ITGB1) Heterodimer Protein, His Tag&Tag Free [IT1-C52W6]

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サプライヤー: AcroBioSystems
カタログNo.: IT1-C52W6
製品名称: Cynomolgus Integrin alpha 3 beta 1 (ITGA3&ITGB1) Heterodimer Protein, His Tag&Tag Free
タンパク質名: Integrin alpha 3 beta 1
Species: Cynomolgus
HOST: HEK293

Synonyms	-
Characteristics	Cynomolgus ITGA3&ITGB1 Heterodimer Protein, His Tag&Tag Free produced by co-expression of ITGA3 and ITGB1, has a calculated MW of 127.5 kDa (ITGA3) & 83.6 kDa (ITGB1). Subunit ITGA3 is fused with an acidic tail at the C-terminus and followed by a polyhistidine tag and subunit ITGB1 contains no tag but a basic tail at the C-terminus. The protein has a calculated MW of 113.1 kDa (ITGA3) & 83.6 kDa (ITGB1). The protein migrates as 110-150 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level	1.0 EU per μg
Purity	90%
Description	Integrin alpha 3 beta 1 is a crucial receptor involved in various biological processes, including cell adhesion, migration, and invasion. It is composed of an alpha subunit (ITGA3) and a beta subunit (ITGB1), which together form the integrin alpha 3 beta 1 complex. This complex plays a significant role in the formation of invadopodia, which are cell membrane protrusions that facilitate cell invasion. The integrin alpha 3 beta 1 complex interacts with various extracellular matrix proteins, such as fibronectin, laminin, and collagen, and is involved in processes like matrix degradation and cell invasion. It is also implicated in the maturation of integrin beta 1, which is essential for cell survival and growth.
Reference	-
URL	https://www.acrobiosystems.com/products/protein/integrin-alpha-3-beta-1-cynomolgus-it1-c52w6

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