Cynomolgus Integrin isoform alpha-7X1B beta 1 (ITGA7X1B&ITGB1) Heterodimer Protein, Tag Free&His Tag (MALS verified) [IT1-C52W3]

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サプライヤー: AcroBioSystems
カタログNo.: IT1-C52W3
製品名称: Cynomolgus Integrin isoform alpha-7X1B beta 1 (ITGA7X1B&ITGB1) Heterodimer Protein, Tag Free&His Tag (MALS verified)
タンパク質名: Integrin isoform alpha-7X1B beta 1
Species: Cynomolgus
HOST: HEK293

Synonyms	-
Characteristics	Cynomolgus ITGA7X1B&ITGB1 Heterodimer Protein, Tag Free&His Tag, produced by co-expression of ITGA7X1B and ITGB1, has a calculated MW of 115.1 kDa (ITGA7X1B) and 85.0 kDa (ITGB1). Subunit ITGA7X1B contains no tag but an acidic tail at the C-terminus and subunit ITGB1 contains a polyhistidine tag and a basic tail at the C-terminus. The non-reducing (NR) protein migrates as 95-115 kDa due to glycosylation.
Endotoxin Level	1.0 EU per μg
Purity	95%
Description	Integrin alpha-7/beta-1 is the primary laminin receptor on skeletal myoblasts and adult myofibers, which is highly expressed in cardiac muscle, skeletal muscle and smooth muscle cells, and localizes to Z-disc and costamere structures. It is involved in the maintenance of the myofibers cytoarchitecture as well as for their anchorage, viability and functional integrity. Isoform Alpha-7X2B and isoform Alpha-7X1B promote myoblast migration on laminin 1 and laminin 2/4, but isoform Alpha-7X1B is less active on laminin 1 (In vitro). ITGA7 has been shown to interact with Merosin, ITGB1, FHL2 and FHL3.
Reference	-
URL	https://www.acrobiosystems.com/products/protein/integrin-isoform-alpha-7x1b-beta-1-cynomolgus-it1-c52w3

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