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タンパク質カタログ
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- サプライヤー
- AcroBioSystems
- カタログNo.
- IR4-C5546
- 製品名称
- Cynomolgus IRAK4 Protein, His Tag (active enzyme)
- タンパク質名
- IRAK4
- Species
- Cynomolgus
- HOST
- InsectCells
Overview
| Synonyms | - |
|---|---|
| Characteristics | This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 53.6 kDa. The protein migrates as 55-60 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation. |
| Endotoxin Level | 1.0 EU per μg |
| Purity | 90% |
| Description | This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene. |
| Reference | - |
| URL | https://www.acrobiosystems.com/products/protein/irak4-cynomolgus-ir4-c5546 |
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