リコンビナントタンパク質
ACROBiosystems社 プロダクトリスト:Recombinant Protein
- サプライヤー
- AcroBioSystems
- カタログNo.
- IN4-H52W3
- 製品名称
- Human Integrin alpha 6 beta 4 Protein, His Tag&Tag Free (MALS verified)
- タンパク質名
- Integrin alpha 6 beta 4
- Species
- Human
- HOST
- HEK293
Overview
Synonyms | - |
---|---|
Characteristics | Human Integrin alpha 6 beta 4 Protein, His Tag&Tag Free, produced by co-expression of ITGA6 and ITGB4, has a calculated MW of 116.8 kDa (ITGA6) and 81.8 kDa (ITGB4). Subunit ITGA6 is fused with an acidic tail at the C-terminus and followed by a polyhistidine tag and subunit ITGB4 contains no tag but a basic tail at the C-terminus. The non-reducing (NR) protein migrates as 130-140 kDa (ITGA6) and 75-85 kDa (ITGB4) respectively due to glycosylation. |
Endotoxin Level | 1.0 EU per μg |
Purity | 95% |
Description | Human integrin alpha(10)I domain as a recombinant protein to reveal its ligand binding specificity. In general, alpha(10)I did recognize collagen types I-VI and laminin-1 in a Mg(2+)-dependent manner, whereas its binding to tenascin was only slightly better than to albumin. Alpha 10 beta 1 is a known collagen-binding I domain integrin, in addition to α1β1, α2β1 and α11β1. GROGER found in the N-terminal domain of collagens I and III, is only weakly recognised by α10β1, an important collagen receptor on chondrocytes, contrasting with the other collagen-binding integrins. |
Reference | - |
URL | https://www.acrobiosystems.com/P5779-Human-Integrin-alpha-6-beta-4-Protein-His-TagTag-Free-%28MALS-verified%29.html |