Cynomolgus Integrin alpha 6 beta 4 (ITGA6&ITGB4) Heterodimer Protein, His Tag&Tag Free (MALS verified) [IN4-C52W3]

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サプライヤー: AcroBioSystems
カタログNo.: IN4-C52W3
製品名称: Cynomolgus Integrin alpha 6 beta 4 (ITGA6&ITGB4) Heterodimer Protein, His Tag&Tag Free (MALS verified)
タンパク質名: Integrin alpha 6 beta 4
Species: Cynomolgus
HOST: HEK293

Synonyms	-
Characteristics	Cynomolgus ITGA6&ITGB4 Heterodimer Protein, His Tag&Tag Free, produced by co-expression of ITGA6 and ITGB4, has a calculated MW of 116.8 kDa (ITGA6) & 82 kDa (ITGB4). Subunit ITGA6 is fused with flag tag at the C-terminus and subunit ITGB4 contains no tag. The protein migrates as 110-130 kDa (ITGA6) and 90-95 kDa (ITGB4) when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level	1.0 EU per μg
Purity	90%
Description	Integrin α6β4 is a key laminin receptor predominantly found in stratified squamous epithelia, especially localized to hemidesmosomes in the basal epidermal layer, where it plays a crucial role in cell-basement membrane adhesion, regulation of keratinocyte motility and polarity, and contributes to the structure of hemidesmosomal plaques, distinguishing it from other integrins.
Reference	-
URL	https://www.acrobiosystems.com/products/protein/integrin-alpha-6-beta-4-cynomolgus-in4-c52w3

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