| Synonyms |
- |
| Characteristics |
Human/Mouse ITGA1&ITGB1 Heterodimer Protein, His Tag&Tag Free, produced by co-expression of ITGA1 and ITGB1, has a calculated MW of 130.0 kDa & 83.5 kDa. The protein migrates as 100-115 kDa and >180 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under non-reducing (NR) condition (SDS-PAGE) due to glycosylation. |
| Endotoxin Level |
1.0 EU per μg |
| Purity |
90% |
| Description |
Integrin alpha-1/beta-1 is a receptor for laminin and collagen. The Integrin alpha-1/beta-1 and Integrin alpha-2/beta-1 integrins provide critical support for vascular endothelial growth factor signaling, endothelial cell migration, and tumor angiogenesis. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. Involved in anchorage-dependent, negative regulation of EGF-stimulated cell growth. |
| Reference |
- |
| URL |
https://www.acrobiosystems.com/P6594-HumanMouse-alpha-1-beta-1-%28ITGA1ITGB1%29-Protein-His-TagTag-Free-%28MALS-verified%29.html |
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