リコンビナントタンパク質
ACROBiosystems社 プロダクトリスト:Recombinant Protein
- サプライヤー
- AcroBioSystems
- カタログNo.
- ILR-H525x
- 製品名称
- Human IL-7 R alpha&TSLP R Heterodimer Protein, Fc Tag&Fc Tag
- タンパク質名
- IL-7 R alpha & TSLP R
- Species
- Human
- HOST
- HEK293
Overview
Synonyms | - |
---|---|
Characteristics | Human IL-7 RA&TSLP R Heterodimer Protein, Fc Tag&Fc Tag is produced by co-expression of IL-7 RA and TSLP R, has a calculated MW of 51.7 kDa (IL-7 RA) and 50.3 kDa (TSLP R). Subunit IL-7 RA is fused with a human IgG1 Fc fragment at the C-terminus and subunit TSLP R is fused with a human IgG1 Fc fragment at the C-terminus. The reducing (R) protein migrates as 60-70 kDa due to glycosylation. |
Endotoxin Level | 1.0 EU per μg |
Purity | 95% |
Description | TSLP is a pleiotropic cytokine originally characterized as a lymphocyte growth factor. Thymic stromal lymphopoietin (TSLP) is overexpressed in the airways of severe asthmatics and is an upstream cytokine that orchestrates inflammatory responses in asthma. Human TSLP exerts its biological activities by binding to a high-affinity heteromeric receptor complex composed of TSLPR and IL- 7 receptor and initiates signaling in cells co-expressing TSLPR and IL-7R. |
Reference | - |
URL | https://www.acrobiosystems.com/P5158-Human-IL-7-R-alphaTSLP-R-Heterodimer-Protein-Fc-TagFc-Tag.html |