検索リコンビナントタンパク質
ACROBiosystems社 プロダクトリスト：Recombinant Protein
- サプライヤー
- AcroBioSystems
- カタログNo.
- ILR-H525b
- 製品名称
- Human IL-4 R alpha & IL-13 R alpha 1 Protein, Fc Tag&Fc Tag (MALS verified)
- タンパク質名
- IL-4 R alpha & IL-13 R alpha 1
- Species
- Human
- HOST
- HEK293
Overview
| Synonyms | - |
|---|---|
| Characteristics | Human IL-4 R alpha & IL-13 R alpha 1 Protein, Fc Tag&Fc Tag is produced by co-expression of IL-4 R alpha and IL-13 R alpha 1, has a calculated MW of 50.2 kDa & 63.1 kDa. The protein migrates as 65-95 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation. |
| Endotoxin Level | 1.0 EU per μg |
| Purity | 95% |
| Description | Interleukin 4 Receptor (IL4R) also known as CD124, IL4Rα and BSF receptor, is a type I cytokine receptor produced by activated Th2 cells and mast cells, and plays an important role in Th2-?biased immune responses, alternative macrophage activation, mucosal immunity, allergic inflammation, tumor progression, and atherogenesis. A soluble form of the encoded IL4R protein can be produced by an alternate splice variant or by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. IL4R can alternatively associate with IL?13Ra1 to form the type II receptor which is responsive to both IL?4 and IL?13. Interleukin-4 receptor has been shown to interact with SHC1. |
| Reference | - |
| URL | https://www.acrobiosystems.com/P7085-Human-IL-4-R-alpha--IL-13-R-alpha-1-Protein-Fc-TagFc-Tag-%28MALS-verified%29.html |
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