Biotinylated Cynomolgus IL-2 R beta&IL-2 R alpha&IL-2 R gamma Protein, Fc,Avitag?&Fc,Avitag? (MALS verified) [ILG-C82F5]

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サプライヤー: AcroBioSystems
カタログNo.: ILG-C82F5
製品名称: Biotinylated Cynomolgus IL-2 R beta&IL-2 R alpha&IL-2 R gamma Protein, Fc,Avitag?&Fc,Avitag? (MALS verified)
タンパク質名: IL-2 R beta & IL-2 R alpha & IL-2 R gamma
Species: Cynomolgus
HOST: HEK293

Synonyms	-
Characteristics	Biotinylated Cynomolgus IL-2RB&IL-2RA&IL-2RG Protein, Fc,Avitag&Fc,Avitag is produced by co-expression of IL-2RB and IL-2RA and IL-2RG, has a calculated MW of 53.0 kDa & 77.4 kDa. Subunit IL-2RB is fused with a human IgG1 Fc tag at the C-terminus, followed by a Avi tag (Avitag?) and subunit IL-2RA&IL-2RG is fused with a human IgG1 Fc tag at the C-terminus, followed by a Avi tag (Avitag?). The protein migrates as 64-70 kDa and 100-130 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level	N/A
Purity	90%
Description	Both Interleukin-2 receptor subunit beta, Interleukin-2 receptor subunit alpha and Interleukin-2 receptor subunit gamma are receptor for interleukin-2. Common subunit for the receptors for a variety of interleukins. Interacts with SHB upon interleukin stimulation. Probably in association with IL15RA, involved in the stimulation of neutrophil phagocytosis by IL15. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit). The high and intermediate affinity forms also associate with a gamma subunit.
Reference	-
URL	https://www.acrobiosystems.com/products/protein/il-2-r-beta-il-2-r-alpha-il-2-r-gamma-cynomolgus-ilg-c82f5

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