Biotinylated Human IL-17A&IL-17F Protein, Avitag?,His Tag [ILF-H82W1]

Synonyms	-
Characteristics	Subunit IL-17A&IL-17F is fused with an Avi tag (Avitag?) at the C-terminus, followed by a polyhistidine tag. This protein has a calculated MW of 34.1 kDa. The reducing (R) protein migrates as 40-43 kDa due to glycosylation.
Endotoxin Level	1.0 EU per μg
Purity	95%
Description	Interleukin-17A (IL17A) is also known as cytotoxic T-lymphocyte-associated antigen 8 (CTLA8),which is a proinflammatory cytokine produced by activated T cells. IL17A can regulate the activities of NF-kappaB and mitogen-activated protein kinases. Also,IL17A can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO).Furthermore,IL17A has been found both in glycosylated and nonglycosylated forms. High levels of IL-17 are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.
Reference	-
URL	https://www.acrobiosystems.com/P2663-Biotinylated-Human-IL-17AIL-17F-Protein-Avitag%E2%84%A2His-Tag.html

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