Human IL-17A&IL-17F Heterodimer Protein, Twin Strep&His Tag (MALS verified) [ILF-H52W6]

サプライヤー: AcroBioSystems
カタログNo.: ILF-H52W6
製品名称: Human IL-17A&IL-17F Heterodimer Protein, Twin Strep&His Tag (MALS verified)
タンパク質名: IL-17A & IL-17F
Species: Human
HOST: HEK293

Synonyms	-
Characteristics	Human IL-17A&IL-17F Heterodimer Protein, Twin Strep&His Tag, produced by co-expression of IL-17A and IL-17F, has a calculated MW of 18.5 kDa (IL-17A) and 16.8 kDa (IL-17F). Subunit IL-17A is fused with a Twin Strep tag at the N-terminus and subunit IL-17F is fused with a polyhistidine tag at the N-terminus. The reducing (R) protein migrates as 19-27 kDa due to glycosylation.
Endotoxin Level	1.0 EU per μg
Purity	90%
Description	Interleukin-17A (IL17A) is also known as cytotoxic T-lymphocyte-associated antigen 8 (CTLA8),which is a proinflammatory cytokine produced by activated T cells. IL17A can regulate the activities of NF-kappaB and mitogen-activated protein kinases. Also,IL17A can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO).Furthermore,IL17A has been found both in glycosylated and nonglycosylated forms. High levels of IL-17 are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.
Reference	-
URL	https://www.acrobiosystems.com/P3882-Human-IL-17AIL-17F-Heterodimer-Protein-Twin-StrepHis-Tag-%28MALS-verified%29.html

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