Biotinylated Mouse IL-2 R alpha / CD25 Protein, His,Avitag? (MALS verified) [ILA-M82E9]

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サプライヤー: AcroBioSystems
カタログNo.: ILA-M82E9
製品名称: Biotinylated Mouse IL-2 R alpha / CD25 Protein, His,Avitag? (MALS verified)
タンパク質名: IL-2 R alpha
Species: Mouse
HOST: HEK293

Synonyms	-
Characteristics	This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag?). The protein has a calculated MW of 28.3 kDa. The protein migrates as 40-60 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level	N/A
Purity	90%
Description	Interleukin-2 receptor subunit alpha (IL2RA) is also known as IL-2R subunit alpha, IL-2-RA, IL2-RA, TAC antigen, p55, CD antigen CD25, is a type I transmembrane glycoprotein. IL2RA is expressed on activated T cells and regulatory T cells, and is capable of binding IL2 with low affinity by itself. However, a ligand-induced high affinity heterotrimeric receptor complex is produced when IL2RA is associated non-covelently with the IL2 receptor beta and gamma chain, and subsequently initiates the intacellular signal pathways such as MAPK or JAK/STAT. On dendritic cells (DC), CD25 has been previously regarded as an activation marker, while both murine and human DC can express CD25, they do not express the beta-chain of the IL-2 receptor, which is indispensable for the execution of IL-2 signaling.
Reference	-
URL	https://www.acrobiosystems.com/products/protein/il-2-r-alpha-mouse-ila-m82e9

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