Human IL-5 R alpha / CD125 Protein, Fc Tag (MALS verified) [ILA-H5269]

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Synonyms	-
Characteristics	This protein carries a human IgG1 Fc tag at the N-terminus. The protein has a calculated MW of 63.2 kDa. The protein migrates as 70-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level	N/A
Purity	95%
Description	Interleukin-5 receptor subunit alpha (IL5RA) is also known as IL-5 receptor subunit alpha, IL-5R subunit alpha and CD125,which is a single-pass type I membrane protein that belongs to the type I cytokine receptor family and type 5 subfamily.IL5R, a heterodimer of an alpha and a beta subunit, is expressed on eosinophils and basophils. IL5RA / CD125 is the receptor for interleukin-5 (IL5) and the alpha chain can bind to IL5. The WSXWS motif of IL5RA appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.The beta subunit of IL5R is common to the IL3, IL5 and GM-CSF receptors.
Reference	-
URL	https://www.acrobiosystems.com/products/protein/il-5-r-alpha-human-ila-h5269

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