Human IL-3 R alpha / CD123 Protein, Llama IgG2b Fc Tag, low endotoxin [ILA-H5255]

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Synonyms	-
Characteristics	This protein carries a llama IgG2b Fc tag at the C-terminus. The protein has a calculated MW of 60.9 kDa. The protein migrates as 45 kDa, 55 kDa and 80 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level	0.01 EU per μg
Purity	90%
Description	Interleukin 3 receptor alpha (low affinity) (IL3RA), also known as CD123 (Cluster of Differentiation 123) is a 70-kD glycoprotein member of the hematopoietin receptor superfamily. This protein associates with a beta subunit common to the receptors for IL-5 and granulocyte-macrophage colony-stimulating factor (GM-CSF) to form a high-affinity receptor for IL-3. The interleukin-3 receptor α chain (CD123) has been identified as a potential immunotherapeutic target because it is overexpressed in AML compared with normal hematopoietic stem cells.
Reference	-
URL	https://www.acrobiosystems.com/products/protein/il-3-r-alpha-human-ila-h5255

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