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タンパク質カタログ
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- サプライヤー
- AcroBioSystems
- カタログNo.
- ILA-C52H3
- 製品名称
- Canine IL-3 R alpha / CD123 Protein, His Tag
- タンパク質名
- IL-3 R alpha
- Species
- Canine
- HOST
- HEK293
Overview
| Synonyms | - |
|---|---|
| Characteristics | This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 34.9 kDa. The protein migrates as 45-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
| Endotoxin Level | 1.0 EU per μg |
| Purity | 90% |
| Description | Interleukin 3 receptor alpha (low affinity) (IL3RA), also known as CD123 (Cluster of Differentiation 123) is a 70-kD glycoprotein member of the hematopoietin receptor superfamily. This protein associates with a beta subunit common to the receptors for IL-5 and granulocyte-macrophage colony-stimulating factor (GM-CSF) to form a high-affinity receptor for IL-3. The interleukin-3 receptor α chain (CD123) has been identified as a potential immunotherapeutic target because it is overexpressed in AML compared with normal hematopoietic stem cells. |
| Reference | - |
| URL | https://www.acrobiosystems.com/products/protein/il-3-r-alpha-canine-ila-c52h3 |
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