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タンパク質カタログ
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- サプライヤー
- AcroBioSystems
- カタログNo.
- IL8-R5113
- 製品名称
- Rhesus macaque IL-18 Protein, Tag Free (MALS & SPR verified)
- タンパク質名
- IL-18
- Species
- Rhesus macaque
- HOST
- E. coli
Overview
| Synonyms | - |
|---|---|
| Characteristics | This protein carries no "tag". The protein has a calculated MW of 18.3 kDa. The protein migrates as 15-17 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE). |
| Endotoxin Level | 1.0 EU per μg |
| Purity | 90% |
| Description | Interleukin-18 (IL-18) is a potent proinflammatory cytokine that induces interferon-gamma (IFN-gamma) production from Th1 cells, NK cells and activated macrophages, particularly in the presence of IL-12. IL-18 also functions in developmental regulation of T-lymphocyte helper type I cells and in Fas-mediated cytotoxicity. Suppression of IL-18 activity is being investigated for treatment of chronic inflammatory diseases such as Crohn's disease and rheumatoid arthritis. It acts by inducing heterodimerization of the two subunits of its receptor, IL-18RAlpha and IL-18RBeta shows structural similarity to IL-1. |
| Reference | 2734 |
| URL | https://www.acrobiosystems.com/products/protein/il-18-rhesus-macaque-il8-r5113 |
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