Human IL-6 R alpha & IL-6 Protein, His Tag (HPLC verified) [IL6-H52H4]

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Synonyms	-
Characteristics	This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 65.0 kDa & 20.8 kDa. The protein migrates as 70-95 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level	1.0 EU per μg
Purity	95%
Description	Interleukin 6 (IL-6) is also known as HGF, BSF2, HSF and IFNB2, originally identified as a B cell differentiation factor, is a multifunctional cytokine that regulates immune responses, hematopoiesis, acute phase responses, and inflammatory reactions.It is secreted by T cells, macrophages , monocytes, fibroblasts, endothelial cells, et.al. to stimulate immune response to trauma, especially burns or other tissue damage leading to inflammation. Interleukin 6 has been shown to interact with interleukin-6 receptor and glycoprotein. IL-6 is relevant to many disease processes such as diabetes, atherosclerosis, depression, Alzheimer's Disease, systemic, lupus erythematosus, prostate cancer and rheumatoid arthritis. Advanced/metastatic cancer patients have higher levels of IL-6 in their blood. Hence there is an interest in developing anti-IL-6 agents as therapy against many of these diseases.
Reference	2706
URL	https://www.acrobiosystems.com/products/protein/il-6-r-alpha-il-6-human-il6-h52h4

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