ナミキ商事株式会社 医薬品及び創薬化学品の専門商社

医薬品及び創薬化学品の専門商社

検索検索

バイオ製品Bio Products

タンパク質(癌免疫療法用)

ACROBiosystems社 プロダクトリスト:Recombinant Protein

サプライヤー
AcroBioSystems
カタログNo.
IL4-H4218
製品名称
ActiveMax Recombinant Human IL-4
タンパク質名
IL-4
Species
Human
HOST
HEK293
20ug: 38,000円
お問い合わせ
50ug: 84,000円
お問い合わせ

Overview

Synonyms IL4,BCGF1,BSF1
Characteristics This protein carries no "tag". The protein has a calculated MW of 14.9 kDa. The protein migrates as 15 and 19 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level Less than 0.1 EU per μg by the LAL method.
Purity >90% as determined by SDS-PAGE.
Description Interleukin-4, is a cytokine that induces differentiation of naive helper T cells (Th0 cells to Th2 cells). In the presence of IL-4 and IL-13, cytokines that are produced in a Th-2 type response, particularly during allergy and parasitic infections, macrophages become differentially activated, And this cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. Recently, researcher found that the cytokine IL-4 plays a key role in development of innate CD8+ T cells in the thymus of several gene-deficient mouse strains, including Itk, KLF2, CBP and Id3, without previous exposure to antigen.
Reference (1) Callard RE., et al., 1991, Br J Haematol. Jul;78(3):293-9.
(2) Varin A, Gordon S., et al., 2009, Immunobiology. 214(7):630-41.
(3) Finkelman FD, et al., 2004, Immunol Rev. 201:139-55.
(4) Lee YJ, Jameson SC,et al., 2011, Trends Immunol. 32(2):50-6. Epub 2011 Feb 1.
URL http://www.acrobiosystems.com/P297-Human-IL-4-Interleukin-4-ProteinHEK293-expressedActiveMax.html

お問い合わせリスト(-)

お問い合わせフォーム